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Tugan Tezcaner, Yahya Ekici, Ozgur Harmanci, Gokhan Moray
Background: Brunner’s gland hamartoma is a rare benign tumor of the duodenum. It may present with either various symptoms caused by obstruction or bleeding; or incidental mass with no symptoms. A 54-years old woman admitted to hospital for melena. Esophagogastroduodenoscopy revealed a large pedunculated polyp arising from distal portion of the duodenal bulb; erosions and hematin coatings was found overlying mucosa. Endoscopic removal was not possible due to its measures and thick stalk. The lesion was resected at the base of stalk with normal mucosa via duodenotomy. Histopathologic examination revealed that this tumor was a Brunner’s gland hamartoma, 5 cm in its greatest dimension. We described a case of Brunner’s gland hamartoma caused upper gastrointestinal bleeding four years after the first diagnosis and related literature was reviewed.