Nuestro grupo organiza más de 3000 Series de conferencias Eventos cada año en EE. UU., Europa y América. Asia con el apoyo de 1.000 sociedades científicas más y publica más de 700 Acceso abierto Revistas que contienen más de 50.000 personalidades eminentes, científicos de renombre como miembros del consejo editorial.
Revistas de acceso abierto que ganan más lectores y citas
700 revistas y 15 000 000 de lectores Cada revista obtiene más de 25 000 lectores
Koji Matsuura and Ikuyo Sugimoto
Human serum albumin (HSA) is used for mammalian embryo culture in assisted reproductive technology (ART) to adjust osmotic pressure and growth factor concentration in culture media. In human serum, transition metal ions, particularly Zn2+, bind to the coordination sites of HSA; thus analyzing the binding of these metal ions may help predict the possible harmful effects of these metals on embryo culture. In this study, we found that metal ions and zincon bound to HSA, and that a complex was formed with the HSA molecule. Using this method, the metals that bind to the multi-binding site of HSA, particularly Zn2+ can be evaluated by colorimetry in an ART laboratory. This analytical method is potentially applicable for metal detection in HSA in ART clinics and also for quick analysis of the coordination of 64Cu2+ with HSA as a probe chemical in positron emission tomography.