Bioquímica y fisiología: acceso abierto

Abstracto

Effect of Exposure to Electromagnetic Fields (Emfs) on Monoamine Neurotransmitters of Newborn Rats

SA Ismail, Rehab FM Ali, Hassan HMM and Abd El-Rahman D

Background: The use of mobile phones is increasing day by day, and spending long time connected has aroused interest of possible interactions reflected on human body by radiofrequency electromagnetic radiation.

Purpose: In the current investigation pregnant female Albino rats were exposed to three mobile phone frequencies (900/1800/2100).

Materials and Methods: After delivery, the newborn rats were also subjected to the same condition of exposition to EMF. Histamine, dopamine, serotonin, melatonin, adrenaline, and noradrenaline in the brain wereassayed by highperformance liquid chromatography.

Results and Conclusions: No significant (p ≥ 0.05) changes in the level of monoamine neurotransmitters were shown for the control rats at different ages. Histamine, dopamine, adrenaline, and noradrenaline contents for the exposed animals were significantly (P ≤ 0.05) increased with increasing exposure time. However, exposure to electromagnetic field EMF caused significant decreases in the serotonin and melatonin content of rat brains.The results concluded that the exposure of new born rats to EMF may be sufficient to induce significant changes in the content of monoamine neurotransmitters of the exposed rats.