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Olfat Gsib, Christophe Egles, and Sidi A Bencherif
The ultimate goal in skin tissue regeneration is to develop covering replacements for the restoration of broken or missing skins in patients also on enhance wound healing processes. Fibrin, a naturally-occurring biopolymer concerned in wound healing has seen widespread use in tissue engineering thanks to its bioactivity, biocompatibility, biodegradability, and facile method ability. However, the versatile biopolymer ought to be additional explored and additional specifically for skin tissue engineering methods thanks to its exceptional skin repair capacity: intrinsic healing properties, all-mains to biomaterial style from its clotting factor and coagulase precursors and tuneable Physico-chemical options. Fibrin’s poor mechanical properties is expeditiously improved by combining the biopolymer with artificial polymers like synthetic resin glycol. The aim of this statement is to supply a cryptic insight on the key properties of protein for skin healing and regeneration, notably light the rising role of fibrin-based Hydrogels as skin substitutes.