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Kim I, Chae H
A retroperitoneal liposarcoma is a rare tumor. It is classified as several subtypes according to the quantity of lipid, mucoid lipid, and the differentiation of cells. When a tumor is histologically composed of well to poorly differentiated liposarcoma and non-lipomatous sarcoma, it is called a dedifferentiated liposarcoma. Although the prognosis of most liposarcomas are better than other sarcomas, dedifferentiated liposarcoma could be life-threatening because of its higher malignant potential. A dedifferentiated retroperitoneal liposarcoma is a rare disease and there are only a few studies reported, especially in Korea and Asian countries. Despite the relative rarity, these tumors can cause significant morbidity and mortality in affected patients, and complete resection is only the principal treatment. Therefore, we report a case of a giant dedifferentiated liposarcoma of the retroperitoneum in a 66-year-old man who underwent complete resection.