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Yung-Sung Yeh, Yu-Ho Huang, Hui-Chen Lin, Ying-Ling Shih, Chien-Yu Lu, Jaw-Yuan Wang
Liposarcoma is a soft tissue sarcoma typically seen in adults, and it usually arises in the limbs or retroperitoneum but rarely has a visceral location. We report here a rare case of long-term recurrent liposarcoma of the anterior mediastinum with gastric metastasis. A 55-year-old male was admitted to hospital with initial presentations of epigastralgia, anorexia, body weight loss and black stool recently. Nine years before this episode, he had received wide excision of a well-differentiated liposarcoma in the anterior mediastinum. After admission, esophagogastroduodenoscopy revealed a submucosal mass with mucosal erosion involving the great curvature of the stomach. A partial gastrectomy was performed and histopathological examination confirmed that the gastric submucosal lesion was a metastasis of the liposarcoma from mediastinum. The patient was finally diagnosed with recurrent mediastinal liposarcoma with gastric metastasis. A review of the medical literature in English till now shows that this is the first reported case of recurrent mediastinal liposarcoma with gastric metastasis.