Nuestro grupo organiza más de 3000 Series de conferencias Eventos cada año en EE. UU., Europa y América. Asia con el apoyo de 1.000 sociedades científicas más y publica más de 700 Acceso abierto Revistas que contienen más de 50.000 personalidades eminentes, científicos de renombre como miembros del consejo editorial.
Revistas de acceso abierto que ganan más lectores y citas
700 revistas y 15 000 000 de lectores Cada revista obtiene más de 25 000 lectores
Lorenzo-Gómez MF, Padilla-Fernández B, Arcila-Piedrahita A, Antúnez-Plaza P, Valverde-Martínez S and Silva-Abuín JM
Introduction: According to the European Urologic Guidelines up to 85% of urothelial cancer of the bladder (UCa) is diagnosed at the non-metastatic stage, being gross haematuria the most common symptom in 70-80% of the cases. This report introduces the case of a T4 G3 metastatic UCa proved to be asymptomatic until its final stage, when an effective treatment is unavailable.
Case report: A 68-year-old male has been presenting dizziness and mild haematuriafor fourteen days before arranging a doctor’s appointment. Physical examination goes as follows: Apyretic, lightly painful, abdomen. Serum creatinine 1.3 mg/dl, Hemoglobin 11.7 gr/dl. Abdominal ultrasound: Both kidneys were standard, bladder contained a heterogeneous mass. History: He remembers a single gross haematuria monosymptomatic episode 12 years before. Three months after the aforementioned episode, a pituitary macroadenoma 7 cm is size was diagnosed and surgically dissected; for this reason, the haematuria drew no attention. The patient had no spouse or close relatives. He had never had other gross haematuria episodes or other urologic symptoms before. Urine cytology: UCa grade 3. Chest radiography: Multiple metastases. Computed Tomography (CT) of thorax-abdomen-pelvis showed pulmonary, pleural, liver, mesenteric and bone metastases; positive lymphatic nodes in pleural membrane and between aorta and lung. Both kidneys were normal. The urinary bladder appeared to be filled with mass. Due to both clinical and personal circumstances, the patient, in agreement with his family, signed up for palliative care only. He passed away out of acute respiratory failure 41 days after the first consult.
Conclusions: Metastatic UCa at diagnosis shows a very poor survival rate. Chemotherapy with methotrexate + vinblastine + adriamicyn + cisplatin can have a success rate of 30%, improving survival to 11-14 months with high toxicity.