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Abstracto

Oxidative Stress Responses in Bufo regularis Tadpole Exposed to Butaforce® and Termex®

Ejilibe CO1, Nwamba HO2, Ani CL2, Madu J3, Onyishi GC3 and Nwani CD3*

The present study investigated the oxidative stress responses of Bufo regularis tadpoles exposed to Butaforce and Termex pesticides. The results indicated that Lipid Peroxidase (LPO), Glutathione peroxidase (GPx), Catalase (CAT), Superoxide Dismutase (SOD), Glutathione Reductase (GR), Reduced Glutathione (GHS) and Glutathione Transferase (GST) in the exposed tadpoles showed significant differences from the control groups. There was a decrease in LPO, GPX, CAT and SOD in the B. regularis tadpole exposed to Butaforce and Termex while an increase in GR, GSH and GST was observed among the treatment compared with the control group. It is possible that Butaforce and Termex metabolism in the B. regularis tadpoles may had generated reactive oxygen species (ROS) that could have interacted with enzymatic activities in the muscle of exposed tadpoles resulting in oxidative stress. The results of the present findings indicated that both pesticides were toxic to B. regularis tadpole resulting in alterations in the oxidatives stress parameters. Both pesticides should be used very carefully to avoid contamination of aquatic environment.