Revista internacional de investigación y desarrollo en farmacia y ciencias biológicas

Abstracto

ANTIOXIDANT ACTIVITY OF NOVEL 4-OXO-AZETIDINE DERIVATIVES SYNTHESIZED FROM SCHIFF BASES

N. Madhavi, B. Lourdu Rani

The synthesized 4-Oxo-Azetidines which are established by spectral and analytical data are evaluated for their antioxidant activity. The activity of all compounds is identified by using nitricoxide and superoxide radical scavenging methods against Alkaline Dimethyl Sulphoxide (DMSO). The derivatives with chlorine substituent either at ortho or para on phenyl ring exhibited maximum activity in both methods. Least activity is shown by the compound having ortho nitro group on benzene ring.