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Effect of bariatric operation on gout disease: literature review and retrospective study on 220 patients

Midhat abu Sneineh

Gout is a common arthritis disease, characterized by high serum levels of uric acid. Many risk factors were found to contribute to the development of the disease. Accumulative evidences have pointed out that gout disease is highly associated with obesity and metabolic syndrome. Moreover, it was demonstrated by various clinical studies that upon major weight loss the risk for the development of gout, as well as the frequency of attacks are reduced in correlation to a reduction in the serum uric acid levels. Bariatric surgery is the most effective means of achieving substantial and sustained weight loss in obese subjects.15 ,16The patient underwent laparoscopic adrenalectomy. Biopsy results demonstrated a brownish yellow lesion, 2.8 cm in diameter, composed of a blood clot and septate. Immunochemical staining for CD31 and CD34 was positive and the lesion was diagnosed as an IPEH of pure form. Our review of literature examines different forms of IPEH, previous reports and characteristics of Masson’s tumors in the adrenal gland and stratifies ways of differentiation it from other benign or malignant lesions of the adrenal.