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Purnima Tripathi, U. Ubaidulla, Roop Kishan Khar, Vishwavibhuti
The aim of writing this review on gastro retentive and floating drug delivery system was to compile the new literature with the principle mechanism of floatation to acquired gastric retention. Various attempts have been made to develop gastroretentive delivery systems such as high density system, swelling, floating system. In floating multiple unit and single unit system are design and their classification and formulation aspect is cover in detail. These systems are very helpful to different problem solve during the formulation of different dosage form. In this review the gastric physiology and reported intra gastric delivery system have briefly been presented.