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Healthcare professionals and patients can access current information on many aspects of drugs through the Drug Information Center (DIC) or Medicine Information Services. By fostering medication knowledge and supporting pharmaceutical services, medicine information services also help to reduce medication errors. This reflective commentary's main goals are to emphasize the current state of Nepal's medical information services, DIC problems,DIC strengthening strategies, and DIC prospects for the future. It is now simpler to evaluate the information in a nation like Nepal thanks to the availability of medicine information on multiple online drug information sites and programmers (apps). Before being shared, this information's veracity and dependability should be examined. By assisting doctors in using pharmaceuticals more safely and encouraging adverse drug reaction (ADR) reporting in Nepal, DIC plays a critical role in enhancing drug safety. There is not enough financial support in Nepal to run the DIC effectively, which causes operational issues. To guarantee the high quality of the service, the effectiveness of the nation's medical information services should be assessed on a regular basis. The government, private hospitals, and regulatory organizations should take action to maintain the current DIC and to build new DICs in the future to offer the community high-quality healthcare services.